2-Aminomethyl-1-ethylpyrrolidine → HCID 70251891, compound

HRID 1637606Notes

Reaction equation

HRID 1637606 reaction equation
[CH2:1]([O:11][C:12]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][C:13]=1[C:14]([OH:16])=O)/[CH:2]=[C:3](/[CH2:5][CH2:6][CH:7]=[C:8]([CH3:10])[CH3:9])\[CH3:4].[NH2:23][CH2:24][CH:25]1[CH2:29][CH2:28][CH2:27][N:26]1[CH2:30][CH3:31]>>[CH2:30]([N:26]1[CH2:27][CH2:28][CH2:29][CH:25]1[CH2:24][NH:23][C:14](=[O:16])[C:13]1[CH:17]=[C:18]([O:21][CH3:22])[CH:19]=[CH:20][C:12]=1[O:11][CH2:1]/[CH:2]=[C:3](/[CH2:5][CH2:6][CH:7]=[C:8]([CH3:9])[CH3:10])\[CH3:4])[CH3:31]

Participants

3

Reactant 2

HCID 1172952-Aminomethyl-1-ethylpyrrolidineHCID 69852996HCID 69852996, compound

Product 1

HCID 70251891HCID 70251891, compoundYield 86%

Procedure

In a manner identical to Example 15, 2-geranyloxy-5-methoxybenzoic acid(1.52 g) was subjected to a condensation reaction with 2-aminomethyl-1-ethylpyrrolidine (0.7 ml), thereby yielding 1.78 g(86%) of the aimed compound.

Sources & evidence

ORD record
ord-949d9b5b157842cda112ff2e78ee292f
Source dataset
uspto-grants-2000_03
Patent number
US06043243

Reaction notes

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