2-Aminomethyl-1-ethylpyrrolidine → HCID 54290102, compound

HRID 1637612Notes

Reaction equation

HRID 1637612 reaction equation
[CH2:1]([O:6][C:7]1[N:15]=[CH:14][CH:13]=[CH:12][C:8]=1[C:9]([OH:11])=O)[CH:2]=[C:3]([CH3:5])[CH3:4].[NH2:16][CH2:17][CH:18]1[CH2:22][CH2:21][CH2:20][N:19]1[CH2:23][CH3:24]>>[CH2:23]([N:19]1[CH2:20][CH2:21][CH2:22][CH:18]1[CH2:17][NH:16][C:9](=[O:11])[C:8]1[CH:12]=[CH:13][CH:14]=[N:15][C:7]=1[O:6][CH2:1][CH:2]=[C:3]([CH3:4])[CH3:5])[CH3:24]

Participants

3

Reactant 2

HCID 1172952-Aminomethyl-1-ethylpyrrolidineHCID 18799496HCID 18799496, compound

Product 1

HCID 54290102HCID 54290102, compoundYield 92%

Procedure

In a manner identical to Example 15, 2-prenyloxynicotinic acid (1.00 g) was subjected to a condensation reaction with 2-aminomethyl-1-ethylpyrrolidine (0.63 g), thereby yielding 1.41 g(92%) of the aimed compound.

Sources & evidence

ORD record
ord-3493b5bca25e4525b444dfd2d99ee61b
Source dataset
uspto-grants-2000_03
Patent number
US06043243

Reaction notes

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