6-[3-(2-Chloromethyl-3-methylpyridin-4-ylsulfanyl)propylsulfanyl]-3-nitroimidazo[1,2-b]pyridazine → 6-{3-[3-Methyl-2-(pyridin-4-ylsulfanylmethyl)-pyridin-4-ylsulfanyl]propylsulfanyl}-3-nitro-imidazo[1,2-b]pyridazine hydrochloride

Participants

Reaction Steps

0.53 g (1.3 mmol) of 6-[3-(2-chloromethyl-3-methylpyridin-4-ylsulfanyl)propylsulfanyl]-3-nitro-imidazo[1,2-b]pyridazine and 0.15 g (1.3 mmol) of 4-mercaptopyridine in 30 ml of isopropanol are reacted as described in Example 2. 0.59 g (87%) of the title compound of m.p. 174-178° C. is isolated.

Provenance & Evidence