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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 163773Generated: October 25, 2026

Water → 6-chloro-5-fluoro-N-methyl-2-(methylthio)-N-(1,3-thiazol-2-ylmethyl)-4-pyrimidinamine

https://huagongshe.com/reaction/163773

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantMethyl((1,3-thiazol-2-yl)methyl)amineHCID 18939834—
Reactant4,6-Dichloro-5-fluoro-2-(methylsulfanyl)pyrimidineHCID 22378277—
Product6-chloro-5-fluoro-N-methyl-2-(methylthio)-N-(1,3-thiazol-2-ylmethyl)-4-pyrimidinamineHCID 86637012—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-5fba7dee3e00469895f479c59e232389
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)