HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → HCID 18799862, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Ammonium Persulfate | HCID 62648 | — |
| Reactant | HCID 12291568 | HCID 12291568 | — |
| Reactant | 2-(Hydroxymethyl)pyridine-4-carbonitrile | HCID 13292599 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 18799862 | HCID 18799862 | 21% |
Reaction Steps
In a manner similar to the procedure described for the preparation of 4-cyano-2-hydroxymethylpyridine, 4-(4-morpholinyl)methylpyridine (9.15 g, 51.40 mmol), ammonium persulfate (23.44 g, 102.81 mmol, 2.0 equiv.), methanol (92 ml), water (46 ml) and concentrated H2SO4 (11.59 g, 118.2 mmol, 2.3 equiv.) provided 2.29 g (21%) of 2-hydroxymethyl-4-(4-morpholinyl)methylpyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06043248 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-f1def804173e4fc1bf7d6479b8baf36a |
| Source note | uspto-grants-2000_03 |