1,10-Dibromodecane → HCID 18800915, compound

HRID 1637794Notes

Reaction equation

HRID 1637794 reaction equation
[CH2:1]([O:8][C:9]1[CH:18]=[C:17]2[C:12]([C@H:13]([C:25]3[CH:30]=[CH:29][C:28]([OH:31])=[CH:27][CH:26]=3)[C@H:14]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:15][O:16]2)=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42]Br>>[CH2:1]([O:8][C:9]1[CH:18]=[C:17]2[C:12]([CH:13]([C:25]3[CH:26]=[CH:27][C:28]([O:31][CH2:42][CH2:41][CH2:40][CH2:39][CH2:38][CH2:37][CH2:36][CH2:35][CH2:34][CH2:33][Br:32])=[CH:29][CH:30]=3)[CH:14]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:15][O:16]2)=[CH:11][CH:10]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 2214831,10-DibromodecaneHCID 86755262HCID 86755262, compound

Product 1

HCID 18800915HCID 18800915, compound

Procedure

From (+,-) cis 7-Benzyloxy-4-(4-hydroxy-phenyl)-3-phenyl-chroman (2 g, 4.9 mmol) and 1,10-Dibromodecane (7.4 g, 24.5 mmol). The product was purified by flash chromatography using petrol ether-ethyl acetate-toluene-methylene chloride 10+0.5+0.5+0.1 as eluent.

Workup

  1. customThe product was purified by flash chromatography

Sources & evidence

ORD record
ord-213479e6a37b4e2a9f4dee18cee6b139
Source dataset
uspto-grants-2000_03
Patent number
US06043269

Reaction notes

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