Morpholine → HCID 86755263, compound

HRID 1637810Notes

Reaction equation

[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([C@H:6]([C:18]3[CH:23]=[CH:22][C:21]([O:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34]Br)=[CH:20][CH:19]=3)[C@H:7]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[CH2:8][O:9]2)=[CH:4][CH:3]=1.[NH:36]1[CH2:41][CH2:40][O:39][CH2:38][CH2:37]1>>[CH2:6]([O:1][C:2]1[CH:11]=[C:10]2[C:5]([C@H:6]([C:18]3[CH:23]=[CH:22][C:21]([O:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][N:36]4[CH2:41][CH2:40][O:39][CH2:38][CH2:37]4)=[CH:20][CH:19]=3)[C@H:7]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[CH2:8][O:9]2)=[CH:4][CH:3]=1)[C:5]1[CH:10]=[CH:11][CH:2]=[CH:3][CH:4]=1

Participants

Reactant 2

HCID 8083Morpholine

HCID 86755264HCID 86755264, compound

Product 1

HCID 86755263HCID 86755263, compound

Procedure

From (+,-) cis 7-Hydroxy-4-[4-(10-Bromodecyloxy)-phenyl]-3-phenyl-chroman (300 mg, 0.48 mmol) and morpholine (208 mg, 2.4 mmol).

Sources & evidence

ORD record: ord-78d8c4bd2742445e8df6178cf87e8fbb
Source dataset: uspto-grants-2000_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06043269

Reaction notes

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