HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrobenzaldehyde → 1-(4-nitrophenyl)-2,3,4,9-tetrahydro-1H-beta-carboline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrobenzaldehyde | HCID 541 | — |
| Reactant | Tryptamine | HCID 1150 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Product | 1-(4-nitrophenyl)-2,3,4,9-tetrahydro-1H-beta-carboline | HCID 3474286 | 86% |
Reaction Steps
This product was prepared using the same procedure as for Intermediate 1 with tryptamine (2.0 g, 12.5 mmol), 4-nitrobenzaldehyde (1.88 g, 1 equiv.) and TFA (1.9 mL, 2 equiv.) to give the title compound (3.1 g, 86%) as a yellow powder. MP: 190° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06043252 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-0e0ff14c25e8451eae3aafd631587e78 |
| Source note | uspto-grants-2000_03 |