HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tryptamine → 2,3,4,9-Tetrahydro-1-(4-methylphenyl)-1H-pyrido[3,4-b]indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tryptamine | HCID 1150 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 4-Methylbenzaldehyde | HCID 7725 | — |
| Product | 2,3,4,9-Tetrahydro-1-(4-methylphenyl)-1H-pyrido[3,4-b]indole | HCID 3352505 | 100% |
Reaction Steps
This product was prepared using the same procedure as for Intermediate 1 with tryptamine (1.0 g, 6.2 mmol), 4-methylbenzaldehyde (0.74 g, 1 equiv.) and TFA (1 mL, 2 equiv.) to give the title compound (1.6 g, 100%) as a white powder. MP: 207-209° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06043252 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-fef35e02808b45f1bfd9ec448876e2e8 |
| Source note | uspto-grants-2000_03 |