HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tryptamine → HCID 10870492, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tryptamine | HCID 1150 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 2,3-Dihydro-1,4-benzodioxin-6-carbaldehyde | HCID 248127 | — |
| Product | HCID 10870492 | HCID 10870492 | 75% |
Reaction Steps
This product was prepared using the same procedure as for Intermediate 1 with tryptamine (4.92 g, 30.7 mmol), 2,3-dihydrobenzo[1,4]dioxin-6-carboxaldehyde (5.05 g, 1.0 equiv.) and TFA (5.0 mL, 2 equiv.) to give the title compound (7.05 g, 75%) as white crystals after recrystallization from iPr2O. MP: 144° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06043252 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-5bd2a53757104598a9d24986ddd8d90d |
| Source note | uspto-grants-2000_03 |