HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tryptamine → HCID 18363087, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tryptamine | HCID 1150 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 3,4-Difluorobenzaldehyde | HCID 588088 | — |
| Product | HCID 18363087 | HCID 18363087 | 82% |
Reaction Steps
This product was prepared using the same procedure as for Intermediate 1 with tryptamine (5.4 g, 33.5 mmol), 3,4-difluorobenzaldehyde (5.0 g, 1.05 equiv.) and TFA (5.2 mL, 2 equiv.) to give the title compound (7.8 g, 82%) as white crystals. MP: 151° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06043252 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-4fce995309bc49dcbd3aab5544fa0c5d |
| Source note | uspto-grants-2000_03 |