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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1637926Generated: November 1, 2026

Sodium Hydroxide → HCID 178517262, compound

https://huagongshe.com/reaction/1637926

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant4-(Pyrrolidin-1-ylmethyl)anilineHCID 776852—
Reactant1-Acetyl-3-{1-ethoxy-1-phenylmethylidene}-5-nitro-2-indolinoneHCID 54280104—
SolventMethanolHCID 887—
SolventDimethylformamideHCID 6228—
ProductHCID 178517262HCID 178517262—

Reaction Steps

Prepared from 1-acetyl-3-{1-ethoxy-1-phenylmethylidene}-5-nitro-2-indolinone and 2 equivalents of 4-(1-pyrrolidinyl-methyl)-aniline, melting point 45-50° C. in DMF followed by treatment with 1N sodium hydroxide solution in MeOH.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06043254
Source datasetuspto-grants-2000_03
ORD IDord-1e2c7b49b51f410a8f153f41f92a1e1a
Source noteuspto-grants-2000_03