5-Methyl-4-(4-nitro-phenyl)-imidazole → 4-(5-Methyl-1H-imidazol-4-yl)aniline

HRID 1637938Notes

Reaction equation

HRID 1637938 reaction equation
[CH3:1][C:2]1[NH:6][CH:5]=[N:4][C:3]=1[C:7]1[CH:12]=[CH:11][C:10]([N+:13]([O-])=O)=[CH:9][CH:8]=1>CO>[NH2:13][C:10]1[CH:9]=[CH:8][C:7]([C:3]2[N:4]=[CH:5][NH:6][C:2]=2[CH3:1])=[CH:12][CH:11]=1

Participants

3

Reactant 1

HCID 235073515-Methyl-4-(4-nitro-phenyl)-imidazole

Product 1

HCID 235076304-(5-Methyl-1H-imidazol-4-yl)aniline

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Prepared by hydrogenation of 5-methyl-4-(4-nitro-phenyl)-imidazole in MeOH on palladium/charcoal (10%) at 20° C. and 3.5 bar.

Sources & evidence

ORD record
ord-6adf231bbd054ff3baa8063eb4657ef8
Source dataset
uspto-grants-2000_03
Patent number
US06043254

Reaction notes

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