Acetone → HCID 18380106, compound

HRID 1638132Notes

Reaction equation

HRID 1638132 reaction equation
[SH:1][CH2:2][C:3]([CH2:5][SH:6])=[CH2:4].[CH3:7][C:8]([CH3:10])=O.[Cl-].[Al+3].[Cl-].[Cl-].O>ClCCl>[CH3:7][C:8]1([CH3:10])[S:6][CH2:5][C:3](=[CH2:4])[CH2:2][S:1]1

Participants

6

Reactant 4

HCID 180AcetoneHCID 962WaterHCID 6451240Aluminum(III) ChlorideHCID 15271515HCID 15271515, compound

Product 1

HCID 18380106HCID 18380106, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2-(Mercaptomethyl)-3-mercapto-1-propene (Z. Chem. 1975, 15, 302)(0.83 g, 6.9 mmoles) and acetone (0.51 mL) were placed in about 15 mL of dichloromethane. Then anhydrous aluminium chloride (0.32 g) was added portionwise over one minute at room temperature. The solution was stirred at room temperature for 30 minutes. The reaction was worked up by addition of 20 mL of water followed by extraction with dichloromethane. The extracts were dried and evaporated to give 0.89 g clear oil with a penetrating smell. The oil was chromatographed to give 400 mg (40%) of clear oil.

Workup

  1. extractionfollowed by extraction with dichloromethane
  2. customThe extracts were dried
  3. customevaporated

Sources & evidence

ORD record
ord-a816314950d0463fb6fa1261bdf91622
Source dataset
uspto-grants-2000_03
Patent number
US06043361

Reaction notes

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