Ammonium Chloride → 2,3,6,7-Tetrahydro-[1,4]oxazepin-5-ylamine monohydrochloride

HRID 1638137Notes

Reaction equation

[O:1]1[CH2:7][CH2:6][C:5](=O)[NH:4][CH2:3][CH2:2]1.[Cl-:9].[NH4+:10]>>[ClH:9].[NH:10]=[C:5]1[CH2:6][CH2:7][O:1][CH2:2][CH2:3][NH:4]1

Participants

Reactant 2

HCID 25517Ammonium Chloride

HCID 70230201,4-Oxazepan-5-one

Product 1

HCID 226177592,3,6,7-Tetrahydro-[1,4]oxazepin-5-ylamine monohydrochloride

Procedure

Employing the procedure in Example 2, step D, tetrahydro-(2H)-1,4-oxazepin-5-one was reacted with Meerwien's salt and ammonium chloride to form hexahydro-5-imino-1H-1,4-oxazepine, hydrochloride.

Sources & evidence

ORD record: ord-ff10c66006314ba3beaea6f022499d6d
Source dataset: uspto-grants-2000_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06043358

Reaction notes

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