Methyl iodide → 8-Cyclodecyl-3-methyl-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one hydrochloride

HRID 1638190Notes

Reaction equation

HRID 1638190 reaction equation
[ClH:1].[CH:2]1([N:12]2[CH2:28][CH2:27][C:15]3([N:19]([C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)[CH2:18][NH:17][C:16]3=[O:26])[CH2:14][CH2:13]2)[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.[CH3:29]I>>[ClH:1].[CH:2]1([N:12]2[CH2:28][CH2:27][C:15]3([N:19]([C:20]4[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=4)[CH2:18][N:17]([CH3:29])[C:16]3=[O:26])[CH2:14][CH2:13]2)[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 19347388HCID 19347388, compound

Product 1

HCID 193474318-Cyclodecyl-3-methyl-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one hydrochloride

Procedure

The title compound, white solid, m.p. 248° C. (dec.) and MS: m/e=384.3 (M+H+) was prepared in accordance with the general method of example 24 from 8-cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4 ,5]decan-4-one hydrochloride and methyl iodide.

Sources & evidence

ORD record
ord-9ddbb3d264564ca696e782fb9b43182d
Source dataset
uspto-grants-2000_03
Patent number
US06043366

Reaction notes

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