5-Chloromethyloxazolidin-2-one → HCID 19347421, compound

HRID 1638208Notes

Reaction equation

HRID 1638208 reaction equation
Cl.[CH:2]1([N:12]2[CH2:28][CH2:27][C:15]3([N:19]([C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)[CH2:18][NH:17][C:16]3=[O:26])[CH2:14][CH2:13]2)[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.[Cl:29][CH2:30][CH:31]1[O:35][C:34](=[O:36])[NH:33][CH2:32]1>>[ClH:29].[CH:2]1([N:12]2[CH2:28][CH2:27][C:15]3([N:19]([C:20]4[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=4)[CH2:18][N:17]([CH2:30][CH:31]4[O:35][C:34](=[O:36])[NH:33][CH2:32]4)[C:16]3=[O:26])[CH2:14][CH2:13]2)[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 908155-Chloromethyloxazolidin-2-oneHCID 19347388HCID 19347388, compound

Product 1

HCID 19347421HCID 19347421, compound

Procedure

The title compound, white solid, m. p. 174° C. and MS: m/e=469.3 (M+H+) was prepared in accordance with the general method of example 24 from 8-cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one hydrochloride and 5-chloromethyl-2-oxazolidinone.

Sources & evidence

ORD record
ord-e9d9e4a134b646cabe87d3e20b06a1e2
Source dataset
uspto-grants-2000_03
Patent number
US06043366

Reaction notes

Loading…