Bromomethyl acetate → HCID 70168949, compound

HRID 1638209Notes

Reaction equation

[ClH:1].[CH:2]1([N:12]2[CH2:28][CH2:27][C:15]3([N:19]([C:20]4[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=4)[CH2:18][NH:17][C:16]3=[O:26])[CH2:14][CH2:13]2)[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.[C:29]([O:32][CH2:33]Br)(=[O:31])[CH3:30]>>[ClH:1].[CH3:33][O:32][C:29](=[O:31])[CH2:30][N:17]1[C:16](=[O:26])[C:15]2([CH2:27][CH2:28][N:12]([CH:2]3[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]3)[CH2:13][CH2:14]2)[N:19]([C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH2:18]1

Participants

Reactant 2

HCID 68536Bromomethyl acetate

HCID 19347388HCID 19347388, compound

Product 1

HCID 70168949HCID 70168949, compound

Procedure

The title compound, white solid, m. p. 178° C. and MS: m/e=442.5 (M+H+) was prepared in accordance with the general method of example 24 from 8-cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4,5]decan-4-one hydrochloride and bromomethyl acetate.

Sources & evidence

ORD record: ord-8d527acc8c7a4110a479c318aeafe600
Source dataset: uspto-grants-2000_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06043366

Reaction notes

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