Hexane → HCID 178506737, compound

HRID 1638277Notes

Reaction equation

HRID 1638277 reaction equation
[CH2:1]([O:7][C:8]1[CH:13]=[CH:12][C:11](Br)=[CH:10][CH:9]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].CCCCCC.C([Li:25])CCC>C1C=CC=CC=1>[CH2:1]([O:7][C:8]1[CH:13]=[CH:12][C:11]([Li:25])=[CH:10][CH:9]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

5

Reactant 3

HCID 8058HexaneHCID 520492Benzene, 1-bromo-4-(hexyloxy)-HCID 178418339Butyllithium

Product 1

HCID 178506737HCID 178506737, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

24.0g (0.093mol) of 4-hexyloxybromobenzene was dissolved in 30ml of benzene and stirred at room temperature in a stream of nitrogen. To the resulting solution was added drop-wise 50ml of hexane solution including 15% of butyllithium was added drop-wise for 30 minutes and the solution was maintained under stirring for 2 hours. The produced precipitate gathered by filtration in a stream of nitrogen was dried under reduced pressure to yield 11.1g of 4-hexyloxyphenyllithium.

Workup

  1. additionwas added drop-wise for 30 minutes
  2. temperaturethe solution was maintained
  3. stirringunder stirring for 2 hours
  4. filtrationThe produced precipitate gathered by filtration in a stream of nitrogen
  5. customwas dried under reduced pressure

Sources & evidence

ORD record
ord-83974357a213486c9870ac8b1419a359
Source dataset
uspto-grants-1989_11
Patent number
US04879060

Reaction notes

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