HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Aminooctanoic acid → HCID 178512800, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Aminooctanoic acid | HCID 66085 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 3,5-Dimethylpyrazole-1-carboxamidine | HCID 97525 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 178512800 | HCID 178512800 | — |
Reaction Steps
3,5-dimethyl-pyrazole-1-carboxamidine (100 g; 0.5 Mole) and N,N-diisopropylethyl amine (DIEA) (65 g; 0.5 Mole) were suspended in dioxane (300 ml) and water (115 ml). 8-Amino-octanoic acid (48 g; 0.3 Mole) was added to the mixture with stirring. The colorless solution was then refluxed for 2 days. The product was filtered and washed with water (3×50 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04879313 |
| Source dataset | uspto-grants-1989_11 |
| ORD ID | ord-66d5fe89126a4fb9ab499452f70f43ca |
| Source note | uspto-grants-1989_11 |