HCID 15670216, compound → HCID 10215074, compound

HRID 1638357Notes

Reaction equation

HRID 1638357 reaction equation
C(SCC(CC1C=CC=CC=1)C(NC1C=C(C=CC=1)C(O)=O)=O)(=O)C1C=CC=CC=1.C([S:34][CH2:35][CH:36]([CH2:49][C:50]1[CH:55]=[CH:54][CH:53]=[CH:52][CH:51]=1)[C:37]([NH:39][C:40]1[CH:48]=[CH:47][C:43]([C:44]([OH:46])=[O:45])=[CH:42][CH:41]=1)=[O:38])(=O)C>>[SH:34][CH2:35][CH:36]([CH2:49][C:50]1[CH:51]=[CH:52][CH:53]=[CH:54][CH:55]=1)[C:37]([NH:39][C:40]1[CH:48]=[CH:47][C:43]([C:44]([OH:46])=[O:45])=[CH:42][CH:41]=1)=[O:38]

Participants

3

Reactant 2

HCID 15670216HCID 15670216, compoundHCID 19842343HCID 19842343, compound

Product 1

HCID 10215074HCID 10215074, compound

Procedure

Using the procedure of Example 3, replace the product of Example 1 with the product of Example 6 to obtain the title compound as a white solid, m.p.=166°-168° C. TLC: Rf=0.6 (silica gel; dichloromethane:methanol:acetic acid, 95:4.5:0.5).

Sources & evidence

ORD record
ord-ffed156405c54641ba751d520975fd80
Source dataset
uspto-grants-1989_11
Patent number
US04879309

Reaction notes

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