2-Chloromethyl-7-(2-trimethylsilanyl-ethoxymethoxy)-naphthalene → HCID 57161469, compound

HRID 163861Notes

Reaction equation

HRID 163861 reaction equation
[C:1]([O:2][C:3]([N:4]1[CH2:5][CH2:6][CH:7]([c:8]2[cH:9][cH:10][c:11]([O:12][CH2:13][CH2:14][CH2:15][O:16][CH2:17][c:18]3[cH:19][cH:20][cH:21][cH:22][c:23]3[O:24][CH3:25])[cH:26][cH:27]2)[CH:28]([OH:29])[CH2:30]1)=[O:31])([CH3:32])([CH3:33])[CH3:34].[C:56]([CH3:57])([CH3:58])([CH3:59])[O:60][C:61](=[O:62])[N:63]1[CH2:64][CH:65]([O:89][CH2:90][c:91]2[cH:92][c:93]3[cH:94][c:95]([O:101][CH2:102][O:103][CH2:104][CH2:105][Si:106]([CH3:107])([CH3:108])[CH3:109])[cH:96][cH:97][c:98]3[cH:99][cH:100]2)[CH:66]([c:69]2[cH:70][cH:71][c:72]([O:75][CH2:76][CH2:77][CH2:78][O:79][CH2:80][c:81]3[c:82]([O:87][CH3:88])[cH:83][cH:84][cH:85][cH:86]3)[cH:73][cH:74]2)[CH2:67][CH2:68]1.[Cl:35][CH2:36][c:37]1[cH:38][cH:39][c:40]2[c:41]([cH:42][c:43]([O:44][CH2:45][O:46][CH2:47][CH2:48][Si:49]([CH3:50])([CH3:51])[CH3:52])[cH:53][cH:54]2)[cH:55]1>>[C:56]([CH3:57])([CH3:58])([CH3:59])[O:60][C:61](=[O:62])[N:63]1[CH2:64][CH:65]([O:89][CH2:90][c:91]2[cH:92][c:93]3[cH:94][c:95]([OH:101])[cH:96][cH:97][c:98]3[cH:99][cH:100]2)[CH:66]([c:69]2[cH:70][cH:71][c:72]([O:75][CH2:76][CH2:77][CH2:78][O:79][CH2:80][c:81]3[c:82]([O:87][CH3:88])[cH:83][cH:84][cH:85][cH:86]3)[cH:73][cH:74]2)[CH2:67][CH2:68]1

Participants

4

Reactant 3

HCID 111630832-Chloromethyl-7-(2-trimethylsilanyl-ethoxymethoxy)-naphthaleneHCID 15546933Tert-butyl 3-hydroxy-4-{4-[3-(2-methoxybenzyloxy) propoxy]phenyl}piperidine-1-carboxylateHCID 54011448(3RS,4RS)-4-[4-[3-(2-methoxy-benzyloxy)-propoxy]-phenyl]-3-[7-(2-trimethylsilanyl-ethoxymethoxy)-naphthalen-2-ylmethoxy]-piperidin-1-carboxylic acid tert-butylester

Product 1

HCID 57161469HCID 57161469, compound

Sources & evidence

ORD record
ord-4676b8edf05d4a128d40fa43b7eb7ab3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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