Benzaldehyde → HCID 19841365, compound

Participants

Reaction Steps

In a round-bottomed flask equipped with a magnetic stirring bar are placed 2 grams of (I) the product of Example 2 (Z= ##STR31## A=N, R=cyclopropyl, R3 =H, R1 =OH), 20 ml of toluene, and 1.5 ml of benzaldehyde. The system is equipped with a Dean-Stark trap containing four angstrom molecular sieves. The reaction mixture is heated at reflux for one day and cooled to room temperature. The solid imine (I) Z= ##STR32## A=N, R=cyclopropyl, R3 =H, R1 =OH) is collected by suction filtration.

Provenance & Evidence