Sodium Acetate → HCID 86743506, compound

HRID 1638734Notes

Reaction equation

HRID 1638734 reaction equation
O.[Br:2][C:3]1[CH:4]=[C:5]([C:9]([CH:11]=O)=[O:10])[CH:6]=[CH:7][CH:8]=1.Cl.[CH3:14][O:15][C:16]1[CH:21]=[CH:20][C:19]([CH2:22][CH:23]([NH:25][OH:26])[CH3:24])=[CH:18][CH:17]=1.C([O-])(=O)C.[Na+]>CO>[Br:2][C:3]1[CH:4]=[C:5]([CH:6]=[CH:7][CH:8]=1)[C:9]([CH:11]=[N+:25]([CH:23]([CH3:24])[CH2:22][C:19]1[CH:20]=[CH:21][C:16]([O:15][CH3:14])=[CH:17][CH:18]=1)[O-:26])=[O:10]

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 1407493892188-54-0HCID 14074940(3-Bromophenyl)(oxo)acetaldehyde--water (1/1)

Product 1

HCID 86743506HCID 86743506, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2.31 g (10 mmol) of 3-bromophenylglyoxal hydrate, 2.175 g (20 mmol) of N-(2-(4-methoxyphenyl)-1-methylethyl)hydroxylamine hydrochloride and 820 mg (10 mmol) of sodium acetate were stirred in 50 ml of absolute methanol at room temperature for 4 hours. After filtration, the fitrate was evaporated, 50 ml of water were added to the residue and the mixture was extracted with methylene chloride (3×25 ml).

Workup

  1. filtrationAfter filtration
  2. customthe fitrate was evaporated
  3. addition50 ml of water were added to the residue
  4. extractionthe mixture was extracted with methylene chloride (3×25 ml)

Sources & evidence

ORD record
ord-616b27466629452a9e8c8bcadfff8aa6
Source dataset
uspto-grants-1989_11
Patent number
US04880840

Reaction notes

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