Acetophenone → 1-Phenylethanol

HRID 1638768Notes

Reaction equation

HRID 1638768 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)(=[O:3])[CH3:2]>S([O-])(O)(=O)=O.C([N+](CCCC)(CCCC)CCCC)CCC>[C:4]1([CH:1]([OH:3])[CH3:2])[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

3

Reactant 1

HCID 7410Acetophenone

Product 1

HCID 74091-PhenylethanolYield 90%

Reagents, catalysts & solvents 1

HCID 94433Tetrabutylammonium hydrogen sulfateCatalyst

Procedure

Under the same conditions, the reduction of acetophenone using tetra-n-butylammonium hydrogensulphate as catalyst gave racemic 1-phenylethanol in 90% yield.

Sources & evidence

ORD record
ord-1a06ebeff48f43b59deda3bb18d52123
Source dataset
uspto-grants-1989_11
Patent number
US04880894

Reaction notes

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