HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 3-Methylazulene-1-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | ethyl 3-acetylindolizine-1-carboxylate | HCID 838368 | — |
| Reactant | HCID 13924938 | HCID 13924938 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Methylazulene-1-carbonyl chloride | HCID 19840208 | — |
Reaction Steps
3-Methyl azulene-1-carbonyl chloride was prepared in situ from 3-methyl azulene-1-carboxylic acid (R. N. McDonald et al., J. Org. Chem., 41, 1822 [1976] by addition of one equivalent of oxalyl chloride to a solution of the acid in dichloromethane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04882327 |
| Source dataset | uspto-grants-1989_11 |
| ORD ID | ord-1bfd657780484f339f55c349c4eee1e3 |
| Source note | uspto-grants-1989_11 |