HCID 178505924, compound → 2-(2-Aminoethylthio)-1-(4-chlorophenyl)imidazole

HRID 1639029Notes

Reaction equation

HRID 1639029 reaction equation
FC1C=[C:4](C=C(F)C=1)[CH2:5][N:6]1C=CN=C1S.[Cl:16][C:17]1[CH:22]=[CH:21][C:20]([N:23]2[CH:27]=[CH:26][N:25]=[C:24]2[SH:28])=[CH:19][CH:18]=1>>[NH2:6][CH2:5][CH2:4][S:28][C:24]1[N:23]([C:20]2[CH:19]=[CH:18][C:17]([Cl:16])=[CH:22][CH:21]=2)[CH:27]=[CH:26][N:25]=1

Participants

3

Reactant 2

HCID 178505924HCID 178505924, compoundHCID 178527867HCID 178527867, compound

Product 1

HCID 198613882-(2-Aminoethylthio)-1-(4-chlorophenyl)imidazole

Procedure

The procedure of Example 1 wherein 1-(3,5-difluorobenzyl)-2-mercaptoimidazole is replaced by 1-(4-chlorophenyl)-2-mercaptoimidazole yields 2-(2-aminoethylthio)-1-(4-chlorophenyl)imidazole.

Sources & evidence

ORD record
ord-236b144aa9b245c6a1164dd9b64636f8
Source dataset
uspto-grants-1989_11
Patent number
US04882348

Reaction notes

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