反应详情

温度

65 °C

To a mixture of 245 g (2 mole) of 3,5-dimethylphenol and 2 liters of 2N sodium hydroxide was added 2.5 moles of 1,4-dichlorobutanol with stirring at 65° C. overnight. The solid precipitate which separated on cooling was filtered and washed with water to neutrality. Recrystallization with isopropyl ether yielded 375 g of white crystalline solid which melted at 74°-76° C.

1. customThe solid precipitate which separated
2. temperatureon cooling
3. filtrationwas filtered
4. washwashed with water to neutrality
5. customRecrystallization with isopropyl ether