4-(Piperazin-1-yl)benzonitrile → 1-Phenoxy-4-[4-(4-cyanophenyl)-1-piperazinyl]-2-butanol

HRID 1639105Notes

Reaction equation

HRID 1639105 reaction equation
Cl[CH2:2][CH2:3][CH:4]([OH:13])[CH2:5][O:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.[N:14]1([C:20]2[CH:27]=[CH:26][C:23]([C:24]#[N:25])=[CH:22][CH:21]=2)[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]1>>[O:6]([CH2:5][CH:4]([OH:13])[CH2:3][CH2:2][N:17]1[CH2:16][CH2:15][N:14]([C:20]2[CH:21]=[CH:22][C:23]([C:24]#[N:25])=[CH:26][CH:27]=2)[CH2:19][CH2:18]1)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 27339954-(Piperazin-1-yl)benzonitrileHCID 131203424-Chloro1-phenoxy-2-butanol

Product 1

HCID 198402321-Phenoxy-4-[4-(4-cyanophenyl)-1-piperazinyl]-2-butanol

Procedure

Following the procedure of Example 25, the title compound is prepared from 4-chloro-1-phenoxy-2-butanol and 4-(1-piperazinyl)benzonitrile.

Sources & evidence

ORD record
ord-e0ab430511444af9ad34ad612e86d757
Source dataset
uspto-grants-1989_11
Patent number
US04882330

Reaction notes

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