Ethyl 4-(piperazin-1-yl)benzoate → 1-Phenoxy-4-[4-(4-ethoxycarbonylphenyl)-1-piperazinyl]-2-butanol

HRID 1639109Notes

Reaction equation

HRID 1639109 reaction equation
[CH2:1]([O:3][C:4](=[O:17])[C:5]1[CH:10]=[CH:9][C:8]([N:11]2[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]2)=[CH:7][CH:6]=1)[CH3:2].Cl[CH2:19][CH2:20][CH:21]([OH:30])[CH2:22][O:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[O:23]([CH2:22][CH:21]([OH:30])[CH2:20][CH2:19][N:14]1[CH2:13][CH2:12][N:11]([C:8]2[CH:7]=[CH:6][C:5]([C:4]([O:3][CH2:1][CH3:2])=[O:17])=[CH:10][CH:9]=2)[CH2:16][CH2:15]1)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 2761178Ethyl 4-(piperazin-1-yl)benzoateHCID 131203424-Chloro1-phenoxy-2-butanol

Product 1

HCID 198402341-Phenoxy-4-[4-(4-ethoxycarbonylphenyl)-1-piperazinyl]-2-butanol

Procedure

Following the procedure of Example 25, the title compound is prepared from 4-(1-piperazinyl)benzoic acid ethyl ester and 4-chloro-1-phenoxy-2-butanol.

Sources & evidence

ORD record
ord-1de36c7dec034adf90cd08dc67e8b197
Source dataset
uspto-grants-1989_11
Patent number
US04882330

Reaction notes

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