1-Bromononane → HCID 14625929, compound

HRID 1639120Notes

Reaction equation

HRID 1639120 reaction equation
[OH:1][CH2:2][CH2:3][N:4]1[CH2:8][CH2:7][CH2:6][C:5]1=[O:9].[CH2:10](Br)[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[OH-].[K+]>CS(C)=O>[CH2:10]([O:1][CH2:2][CH2:3][N:4]1[CH2:8][CH2:7][CH2:6][C:5]1=[O:9])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

Participants

5

Reactant 3

HCID 127421-BromononaneHCID 14797Potassium HydroxideHCID 769801-(2-Hydroxyethyl)-2-pyrrolidinone

Product 1

HCID 14625929HCID 14625929, compoundYield 92.9%

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

1.29 g of 1-(2-hydroxyethyl)-2-pyrrolidone, 4.14 g of n-nonylbromide, 2.24 g of potassium hydroxide in a powder state and 30 ml of dimethyl sulfoxide were mixed together and agitated at room temperature for a whole day. The resulting reaction mixture was extracted with dichloromethane, after which the thus obtained extract was washed with water, dried, feed from the solvent by distillation off and then finally distilled to obtain 2.37 g of colorless 1-[2-(n-nonyloxy) ethyl] azacyclopentane-2-one having the following appearance, column temperature and analysis:

Workup

  1. customThe resulting reaction mixture
  2. extractionwas extracted with dichloromethane
  3. customafter which the thus obtained
  4. extractionextract
  5. washwas washed with water
  6. customdried
  7. distillationfeed from the solvent by distillation off and
  8. distillationthen finally distilled

Sources & evidence

ORD record
ord-5bd4896b0bf64f4a8382135455e9001a
Source dataset
uspto-grants-1989_11
Patent number
US04882359

Reaction notes

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