HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → HCID 14477521, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | 5-[(4-Nitrophenyl)methoxy]-4,5-dioxopentanoate | HCID 22166415 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 14477521 | HCID 14477521 | 43.4% |
Reaction Steps
Phenol (941 mg), 1-(4-nitrobenzyl) 2-oxoglutarate (3.09 g) and DCC (2.27 g) were dissolved in 100 ml of dichloromethane and stirred for 3 hours at room temperature. The precipitated crystals were filtered off and the filtrate was subjected to silica gel column chromatography eluting with dichloromethane-ethyl acetate (3:1) to obtain 1.55 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04882434 |
| Source dataset | uspto-grants-1989_11 |
| ORD ID | ord-63700a705c5d439997273daf80ffc2f5 |
| Source note | uspto-grants-1989_11 |