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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1639169Generated: November 2, 2026

Iodoacetic Acid → Diethyl 2-[(iodoacetyl)amino]malonate

https://huagongshe.com/reaction/1639169

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodoacetic AcidHCID 5240—
ReactantPropanedioic acid, 2-amino-, 1,3-diethyl esterHCID 81272—
ProductDiethyl 2-[(iodoacetyl)amino]malonateHCID 15096465—

Reaction Steps

Diethyl 2-aminomalonate and iodoacetic acid are treated in the same manner as described in Reference Example 1 to give diethyl 2-[(iodoacetyl)amino]malonate, m.p. 96°-98° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04882447
Source datasetuspto-grants-1989_11
ORD IDord-3014e318e731428a9a99bd718c921f77
Source noteuspto-grants-1989_11