HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2,6-difluoroaniline → 4-Amino-3,5-difluorobenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2,6-difluoroaniline | HCID 610191 | — |
| Reactant | HCID 178418546 | HCID 178418546 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | 4-Amino-3,5-difluorobenzonitrile | HCID 280467 | — |
Reaction Steps
The 4-bromo-2,6-difluoroaniline (5) is reacted with copper (I) cyanide in N-methyl-2-pyrrolidone to yield 4-cyano-2,6-difluoroaniline (6).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04883609 |
| Source dataset | uspto-grants-1989_11 |
| ORD ID | ord-be436ca80b274347a786970124c40502 |
| Source note | uspto-grants-1989_11 |