Sodium Hydroxide → HCID 19833129, compound

Participants

Reaction Steps

1.57 g (0.042 mol) of lithium aluminum hydride are suspended in 60 ml of tetrahydrofuran under argon, 5.56 g (0.021 mol) of 8,9-dichloro-1,4,5,6-tetrahydrobenzo[f]-quinolin-3(2H)-one are slowly added thereto and the mixture is boiled under reflux for 2.5 hours. The mixture is then cooled to 0°, 5.2 ml of 18 percent sodium hydroxide solution are added dropwise thereto and the precipitate formed is removed by filtration. On evaporation of the filtrate, there is obtained 8,9-dichloro-1,2,3,4,5,6-hexahydrobenzo[f]quinoline as a yellow oil which is processed directly.

Provenance & Evidence