Diethyl Ether → HCID 19839085, compound

Participants

Reaction Steps

A solution of 52.7 g of methacrylyl chloride in 570 ml of methylene chloride is added dropwise to a stirred solution, cooled to 0°-5° C., of 71 g of N-tert-butyl-methacrylamide, 50.8 g of triethylamine and 570 ml of methylene chloride. After the addition, the mixture is stirred for 2 1/2 hours and the reaction solution is left to stand for 4 days. The concentrated reaction material is taken up in 0.5 1 of diethyl ether, the mixture is filtered and the solution is concentrated. The red oil obtained is filtered with hexane-diethyl ether (4:1) on silica gel to give the title compound as a white crystalline product (m.p. 47°-48° C).

Provenance & Evidence