反应详情

温度

20 °C

To a solution of 1 g of 2-amino-1,3-benzothiazol-6-ol in 66 cm3 of aqueous 0.1N sodium hydroxide solution are added 1.279 g of 2,6-difluorobenzenesulfonyl chloride. The solution is stirred for 5 days at a temperature in the region of 20° C. After addition of 10 cm3 of water, the precipitate is filtered off by suction and then washed with twice 3 cm3 of ice-cold water and dried under reduced pressure over phosphorus pentoxide. 2.1 g of 2-amino-1,3-benzothiazol-6-yl 2,6-difluorobenzenesulfonate are obtained in the form of a pink powder, the characteristics of which are as follows:

1. filtrationthe precipitate is filtered off by suction
2. washwashed with twice 3 cm3 of ice-cold water
3. dry with materialdried under reduced pressure over phosphorus pentoxide