3-Pyridinylboronic acid → 5-Methyl-4-[2-(2-methylpyrrolidin-1-yl)ethyl]-2-(4-pyridin-3-ylphenyl)-1,3-oxazole

HRID 163967Notes

Reaction equation

HRID 163967 reaction equation
[Br:10][c:11]1[cH:12][cH:13][c:14](-[c:17]2[o:18][c:19]([CH3:30])[c:20]([CH2:22][CH2:23][N:24]3[CH:25]([CH3:29])[CH2:26][CH2:27][CH2:28]3)[n:21]2)[cH:15][cH:16]1.[n:1]1[cH:2][c:3]([B:7]([OH:8])[OH:9])[cH:4][cH:5][cH:6]1>>[n:1]1[cH:2][c:3](-[c:11]2[cH:12][cH:13][c:14](-[c:17]3[o:18][c:19]([CH3:30])[c:20]([CH2:22][CH2:23][N:24]4[CH:25]([CH3:29])[CH2:26][CH2:27][CH2:28]4)[n:21]3)[cH:15][cH:16]2)[cH:4][cH:5][cH:6]1

Participants

3

Reactant 2

HCID 27343783-Pyridinylboronic acidHCID 117100152-(4-Bromophenyl)-5-methyl-4-[2-(2-methylpyrrolidin-1-yl)ethyl]-1,3-oxazole

Product 1

HCID 687020355-Methyl-4-[2-(2-methylpyrrolidin-1-yl)ethyl]-2-(4-pyridin-3-ylphenyl)-1,3-oxazole

Sources & evidence

ORD record
ord-cf592cbfa642497993deae0a2b16d7a3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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