HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → HCID 59324119, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 59324097 | HCID 59324097 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 59324119 | HCID 59324119 | — |
Reaction Steps
2-[1-(2,3-dimethyl-phenoxy)-but-3-enyl]-4,5-dihydro-imidazole-1-carboxylic acid tert-butyl ester (120 mg) was dissolved in a solution of 10% trifluoroacetic acid in dichloromethane (5 ml). After 24 hours the mixture was shaken between NaOH (2M) and EtOAc and the organic phase dried with Na2SO4 and evaporated to yield 2-[1-(2,3-Dimethyl-phenoxy)-but-3-enyl]-4,5-dihydro-1H-imidazole as crystals m.p. 72-74° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08110593B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-367966901a094520b223db9ab3d20280 |
| Source note | uspto-grants-2012_02 |