HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triisopropyl borate → 3-(Benzyloxy)-4-(trifluoromethyl)phenylboronic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triisopropyl borate | HCID 21531 | — |
| Reactant | 2-(Benzyloxy)-4-iodo-1-(trifluoromethyl)benzene | HCID 66721024 | — |
| Reactant | HCID 178418918 | HCID 178418918 | — |
| Product | 3-(Benzyloxy)-4-(trifluoromethyl)phenylboronic acid | HCID 56776618 | 79% |
Reaction Steps
According to the method described in example 4.2, starting from 8 g (21.2 mmol) of 2-(benzyloxy)-4-iodo-1-(trifluoromethyl)benzene, 11.1 mL (22.2 mmol) of iPrMgCl and 5 mL (21.6 mmol) of triisopropyl borate, we obtain 4.95 g of [3-(benzyloxy)-4-(trifluoromethyl)phenyl]boronic acid in the form of oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08110579B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-b2d6d44e681e418bba527224cd2d6e39 |
| Source note | uspto-grants-2012_02 |