HCID 58902436, compound → HCID 58902350, compound

Participants

Reaction Steps

A solution of [tert-butyl {4-[(7-{[(3-tert-butylphenyl)amino]carbonyl}-2-naphthyl)oxy]pyridin-2-yl}carbamate (1.05 g, 2.05 mmol;) in 4M HCl in 1,4-dioxane (40 mL) was allowed to stir under an atmosphere of nitrogen for 3 h. The solvents were evaporated to give 7-[(2-aminopyridin-4-yl)oxy]-N-(3-tert-butylphenyl)-2-naphthamide (977 mg, 98%).

Provenance & Evidence