HCID 58902451, compound → HCID 58902461, compound

Participants

Reaction Steps

A solution of tert-butyl {6-[(2-cyanopyridin-4-yl)oxy]-3,4-dihydro-2-H-chromen-3-yl}carbamate in 2M HCl in dioxane (8 mL) was allowed to stir at rt overnight. The reaction mixture was concentrated and the residue was purified by column chromatography to give 4-[(3-amino-3,4-dihydro-2H-chromen-6-yl)oxy]pyridine-2-carbonitrile (0.17 g, 12%).

Provenance & Evidence