HCID 58902242, compound → HCID 58902268, compound

Participants

Reaction Steps

A solution of tert-butyl 7-({2-[(cyclopropylcarbonyl)amino]pyridin-4-yl}oxy)-3,4-dihydroisoquinoline-2(1H)-carboxylate (2.22 g, 0.0051 mol) in 4M of HCl in 1,4-Dioxane (20 mL) was allowed to stir at rt for 30 min. The reaction mixture was concentrated to give N-[4-(1,2,3,4-tetrahydroisoquinolin-7-yloxy)pyridin-2-yl]cyclopropanecarboxamnide. LCMS: (FA) ES+310.3.

Provenance & Evidence