HRID1640375

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)c1ccc([S+](c2ccccc2)c2ccccc2)cc1.[Br-]

HCID22625536

(4-tert-Butylphenyl)(diphenyl)sulfanium bromide

C22H23BrS

结构：CC(C)(C)C(=O)OCC(F)(F)S(=O)(=O)[O-].[Na+]

HCID57817346

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)C(=O)OCC(F)(F)S(=O)(=O)[O-].CC(C)(C)c1ccc([S+](c2ccccc2)c2ccccc2)cc1

HCID86632754

未命名化合物

收率 79%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

In 150 g of dichloromethane were dissolved 20 g (0.052 mole) of sodium 2-pivaloyloxy-1,1-difluoroethanesulfonate (purity 70%) and 217 g (0.052 mole) of an aqueous solution of 4-tert-butylphenyldiphenylsulfonium bromide. The organic layer was separated and washed with 50 g of water three times. The organic layer was concentrated and diethyl ether was added to the residue for recrystallization. The target compound was obtained as white crystals. 26 g (yield 79%).

WORKUP

后处理

customThe organic layer was separated
washwashed with 50 g of water three times
concentrationThe organic layer was concentrated
additiondiethyl ether was added to the residue for recrystallization
customThe target compound was obtained as white crystals

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ac38d62b52ff43b4a1b7cb332feccfbc
来源数据集: uspto-grants-2012_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08114571B2
来源说明: uspto-grants-2012_02

反应 SMILES

[C:1]([O:7][CH2:8][C:9]([F:15])([F:14])[S:10]([O-:13])(=[O:12])=[O:11])(=[O:6])[C:2]([CH3:5])([CH3:4])[CH3:3].[Na+].[Br-].[C:18]([C:22]1[CH:27]=[CH:26][C:25]([S+:28]([C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)[C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)=[CH:24][CH:23]=1)([CH3:21])([CH3:20])[CH3:19]>ClCCl>[C:1]([O:7][CH2:8][C:9]([F:15])([F:14])[S:10]([O-:13])(=[O:11])=[O:12])(=[O:6])[C:2]([CH3:5])([CH3:4])[CH3:3].[C:18]([C:22]1[CH:27]=[CH:26][C:25]([S+:28]([C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)[C:29]2[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=2)=[CH:24][CH:23]=1)([CH3:21])([CH3:19])[CH3:20]