HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Dimethylethylenediamine → N4-(2-(dimethylamino)ethyl)-N6-(5-methyl-1H-pyrazol-3-yl)-2-styrylpyrimidine-4,6-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Dimethylethylenediamine | HCID 66053 | — |
| Reactant | 3-Phenylprop-2-enenitrile | HCID 74667 | — |
| Reactant | 1H-Pyrazol-3-amine, 5-methyl- | HCID 93146 | — |
| Product | N4-(2-(dimethylamino)ethyl)-N6-(5-methyl-1H-pyrazol-3-yl)-2-styrylpyrimidine-4,6-diamine | HCID 86613123 | — |
Reaction Steps
Example 66 was synthesized via Scheme 6 according to the general scheme provided above with the appropriate starting materials cinnamonitrile, 5-methyl-1H-pyrazole-3-amine, and N1,N1-dimethylethane-1,2-diamine. Structure of the target was confirmed by 1H-NMR. The 1H-NMR is attached.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08114870B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-b8bc8ee214f348f0b88bd5f520266c76 |
| Source note | uspto-grants-2012_02 |