Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Phenylprop-2-enenitrile → N-(5-methyl-1H-pyrazol-3-yl)-6-(4-methylsulfonylpiperazin-1-yl)-2-styrylpyrimidin-4-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Phenylprop-2-enenitrile | HCID 74667 | — |
| 반응물 | 1H-Pyrazol-3-amine, 5-methyl- | HCID 93146 | — |
| 반응물 | 1-(Methylsulfonyl)piperazine | HCID 709161 | — |
| 생성물 | N-(5-methyl-1H-pyrazol-3-yl)-6-(4-methylsulfonylpiperazin-1-yl)-2-styrylpyrimidin-4-amine | HCID 66738751 | — |
반응 단계
Example 71 was synthesized via Scheme 6 according to the general scheme provided above with the appropriate starting materials cinnamonitrile, 5-methyl-1H-pyrazole-3-amine, and 4-methylsulfonylpiperazine. Structure of the target was confirmed by 1H-NMR. The 1H-NMR is attached.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08114870B2 |
| 출처 데이터셋 | uspto-grants-2012_02 |
| ORD ID | ord-b45a4f3bcf5c402fb384ce43081c2e16 |
| 출처 메모 | uspto-grants-2012_02 |