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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1640433Generated: October 30, 2026

Pyrrolidine → N-(5-methyl-1H-pyrazol-3-yl)-6-(pyrrolidin-1-yl)-2-styrylpyrimidin-4-amine

https://huagongshe.com/reaction/1640433

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
Reactant3-Phenylprop-2-enenitrileHCID 74667—
Reactant1H-Pyrazol-3-amine, 5-methyl-HCID 93146—
ProductN-(5-methyl-1H-pyrazol-3-yl)-6-(pyrrolidin-1-yl)-2-styrylpyrimidin-4-amineHCID 66738927—

Reaction Steps

Example 76 was synthesized via Scheme 6 according to the general scheme provided above with the appropriate starting materials cinnamonitrile, 5-methyl-1H-pyrazole-3-amine, and pyrrolidine. Structure of the target was confirmed by 1H-NMR. The 1H-NMR is attached.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08114870B2
Source datasetuspto-grants-2012_02
ORD IDord-27a85627dd014e2496015b62b925c9d0
Source noteuspto-grants-2012_02