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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1640434Generated: October 25, 2026

Aniline → N4-(5-methyl-1H-pyrazol-3-yl)-N6-phenyl-2-styrylpyrimidine-4,6-diamine

https://huagongshe.com/reaction/1640434

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnilineHCID 6115—
Reactant3-Phenylprop-2-enenitrileHCID 74667—
Reactant1H-Pyrazol-3-amine, 5-methyl-HCID 93146—
ProductN4-(5-methyl-1H-pyrazol-3-yl)-N6-phenyl-2-styrylpyrimidine-4,6-diamineHCID 86613124—

Reaction Steps

Example 82 was synthesized via Scheme 6 according to the general scheme provided above with the appropriate starting materials cinnamonitrile, 5-methyl-1H-pyrazole-3-amine, and aniline. Structure of the target was confirmed by 1H-NMR. The 1H-NMR is attached.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08114870B2
Source datasetuspto-grants-2012_02
ORD IDord-f48e653961f741738376a32d0cfd467a
Source noteuspto-grants-2012_02