HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Ethynylimidazo[1,2-b]pyridazine → N-(3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylphenyl)-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Ethynylimidazo[1,2-b]pyridazine | HCID 46838760 | — |
| Reactant | N-(3-Iodo-4-methylphenyl)-4-((4methylpiperazin-1-yl) methyl)-3-(trifluoromethyl)benzamide | HCID 46838911 | — |
| Product | N-(3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylphenyl)-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamide | HCID 24826798 | — |
Reaction Steps
The title compound was synthesized from 3-ethynylimidazo[1,2-b]pyridazine and N-(3-iodo-4-methylphenyl)-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamide in a manner similar to that described for Example 14. The product was obtained as a solid: 533 m/z (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08114874B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-fee843f617ae4cd3ae2be473f0100c29 |
| Source note | uspto-grants-2012_02 |