HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acrylate → HCID 66737270, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acrylate | HCID 8821 | — |
| Reactant | 5-Bromo-3-methoxyquinoline | HCID 58227851 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | MeOH tetrahydrofuran | HCID 21899815 | — |
| Product | HCID 66737270 | HCID 66737270 | — |
Reaction Steps
This compound was synthesised from 5-bromo-3-methoxy-quinoline (5.0 g, 21 mmol; prepared as in DE 10316081) and ethyl acrylate (5 eq.) according to method G followed by hydrogenation over Pd/C in THF/MeOH 4:1. The hydrolysis was carried out according to method F. The product was isolated as a colourless solid (0.1 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08114867B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-8a80e0386776407b86001d0b5e5d6437 |
| Source note | uspto-grants-2012_02 |